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15 Night Panama Canal Eastward Cruise
Royal Caribbean International — Serenade of the Seas

15 Night Panama Canal Eastward Cruise

Departs Thu 07/10/2027
Duration 15 Nights
Ship Serenade of the Seas
From San Diego, California
Arrives Tampa, Florida
Region Panama Canal
Day by Day

Ports of Call & Itinerary

15-night voyage departing San Diego, California, arriving Tampa, Florida.

Printable Itinerary (PDF)

Route Map

15 Night Panama Canal Eastward Cruise

7 ports plotted · click a marker for details

Day 1

San Diego, California , United States

Thursday, 07/10/2027

🚢 Departs 17:00

San Diego is a vacationer's paradise, with year-round temperatures in the seventies and near-constant sunshine. One of America's most family-friendly cities, San Diego is home to LEGOLAND, the New Children's Museum, and the famous San Diego Zoo. Sunbathers and surfers are guaranteed to find their perfect beach, and foodies find delights in artisanal breweries, local bistros, and gourmet restaurants. From the Broadway excitement of La Jolla Playhouse to the European feel of Little Italy to the nouveau-chic of the Gaslamp Quarter, San Diego has something for everyone.

San Diego, California

Day 4

Puerto Vallarta , Mexico

Sunday, 10/10/2027

⚓ Arrives 08:00 🚢 Departs 17:00

Puerto Vallarta is a resort town on Mexico’s Pacific coast, in Jalisco state. It is known for its beaches, water sports and nightlife scene. Its cobblestone center is home to the ornate Nuestra Señora de Guadalupe church, boutique shops and a range of restaurants and bars. El Malecón is a beachside promenade with contemporary sculptures, as well as bars, lounges and nightclubs.

Puerto Vallarta

Day 7

Puerto Quetzal , Guatemala

Wednesday, 13/10/2027

⚓ Arrives 08:00 🚢 Departs 17:00

Puerto Quetzal is Guatemala's largest Pacific Ocean port. It is important for both cargo traffic and as a stop-off point for cruise liners

Puerto Quetzal

Day 9

Puntarenas , Costa Rica

Friday, 15/10/2027

⚓ Arrives 08:00 🚢 Departs 17:00

This town is not on the Nicoya Peninsula, but rather on Costa Rica's mainland. It is best known as a cruise-ship port and launching pad for ferries heading southeast to the coast of the Nicoya Peninsula and for cruises sailing out on the Gulf of Nicoya. Puntarenas is also a major fishing port with a lively fish market. The town’s reputation suffers from the unimpressive parts you see from your car as you roll through town on the way to the ferry dock. But the town has a lot of character off the main drag, thanks to its illustrious past as an affluent port town and principal vacation spot for San José's wealthy, who arrived by train in the last century. Once the port was moved and roads opened to other beaches, Puntarenas's economy crashed, but it's making a comeback. Sitting on a narrow spit of sand—punta de arenas literally means "point of sand"—that protrudes into the Gulf of Nicoya, the town boasts a beautifully groomed, wide Blue Flag beach with views of the Nicoya Peninsula and spectacular sunsets, along with a public swimming pool, the San Lucas Beach Club, and a marine-life museum. Ticos arrive by bus and car to enjoy the beach and stroll the Paseo de los Turistas, a beachfront promenade lined with tree-shaded concrete benches and seafood restaurants. Crowds of locals, called porteños, cruise by on bicycles, the town’s most popular form of transport.

Puntarenas

Day 11

Panama Canal Transit

Sunday, 17/10/2027

⚓ Arrives 06:00 🚢 Departs 18:00

Day 12

Cartagena , Colombia

Monday, 18/10/2027

⚓ Arrives 11:30 🚢 Departs 19:00

Cartagena's magnificent city walls and fortresses, now a UNESCO World Heritage Site, enclose a well-restored historic center (the Cuidad Amurallada, or walled city) with plazas, churches, museums, and shops that have made it a lively coastal vacation spot for South Americans and others. New hotels and restaurants make the walled city a desirable place to stay, and the formerly down-at-the-heels Getsemaní neighborhood attracts those seeking a bohemian buzz. The historic center is a small section of Cartagena; many hotels are in the Bocagrande district, an elongated peninsula where high-rise hotels overlook a long, gray-sand beach.When it was founded in 1533 by Spanish conquistador Pedro de Heredia, Cartagena was the only port on the South American mainland. Gold and silver looted from indigenous peoples passed through here en route to Spain and attracted pirates, including Sir Francis Drake, who in 1586 torched 200 buildings. Cartagena's walls protected the city's riches as well as the New World's most important African slave market.

Cartagena

Day 14

Georgetown, Grand Cayman , Cayman Islands

Wednesday, 20/10/2027

⚓ Arrives 07:00 🚢 Departs 16:00

Begin exploring the capital by strolling along the waterfront Harbour Drive to Elmslie Memorial United Church, named after the first Presbyterian missionary to serve in Cayman. Its vaulted ceiling, wooden arches, and sedate nave reflect the religious nature of island residents. In front of the court building, in the center of town, names of influential Caymanians are inscribed on the Wall of History, which commemorates the islands' quincentennial in 2003. Across the street is the Cayman Islands Legislative Assembly Building, next door to the 1919 Peace Memorial Building. In the middle of the financial district is the General Post Office, built in 1939. Let the kids pet the big blue iguana statues.

Georgetown, Grand Cayman

Day 16

Tampa, Florida , United States

Friday, 22/10/2027

⚓ Arrives 05:00

Home to a large number of museums, and often considered one of the best destinations for the arts in the US, Tampa is a must see for anyone interested in the arts, contemporary or older. The Museum of Science and Industry is also an interesting tourist attractions to visit, especially with children.

Tampa, Florida
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✓ One Single Bed ✓ Shower ✓ Toiletries Provided ✓ Room Service Available ✓ Wi-Fi (Additional Cost) ✓ Safe ✓ Hair Dryer ✓ Telephone
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Connecting Ocean View

170 sqft · Up to 2 guests

Experience a spectacular view for a memorable holiday.SizeStateroom: 170 sq. ft. or 15.79 sq. m.BedsTwo twin beds that convert to a Royal King bedOccupancyUp to 2 guestsViewsOcean ViewRoomsRoom with bed, dresser and sitting area with sofaBathroomsOne bathroom
✓ King or Twin Configuration ✓ Lounge Area ✓ Shower ✓ Toiletries Provided ✓ Room Service Available ✓ TV ✓ Wi-Fi (Additional Cost) ✓ Safe

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Serenade of the Seas

Dive into new discoveries as you sail onboard Serenade of the Seas®.

Serenade of the Seas
2,476
Passengers
90,090
Gross Tonnage
2003
Year Built
12
Decks
1,073
Cabins
848
Crew

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